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Real members of MyEczemaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Dermatologist told me oral one can cause cancer. Cream shouldn't, but my thinking is skin takes in what we put on it. I have atopic dermatitis mild to severe when it flares.

September 20, 2024
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A MyEczemaTeam Member

Yes for months it's not for eczema but to restore pigment lost due to vitiligo! The risks outweigh the benefits!!!

September 20, 2024
MyEczemaTeam

Opzelura (ruxolitinib) is a topical cream approved for the treatment of mild to moderate atopic dermatitis in non-immunocompromised individuals aged 12 and older. It is intended for those whose condition isn't adequately controlled with other topical prescription therapies or when those therapies aren't advisable.

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Opzelura (ruxolitinib) is a topical cream approved for the treatment of mild to moderate atopic dermatitis in non-immunocompromised individuals aged 12 and older. It is intended for those whose condition isn't adequately controlled with other topical prescription therapies or when those therapies aren't advisable.

Key Points About Opzelura:
- Application: Apply a thin layer twice daily to the affected areas. It should not be used in the eyes, orally, or intravaginally.
- Body Surface Area: Can be applied to up to 20% of the body surface area.
- Common Side Effects: Nasopharyngitis (common cold), diarrhea, bronchitis, ear infection, increased eosinophil count, hives, folliculitis, tonsillitis, and runny nose.
- Serious Side Effects: Rare but serious side effects include serious infections, higher rates of all-cause mortality, lymphoma and other cancers, major adverse cardiovascular events, and thrombosis.

Considerations:
- Absorption: While the cream is topical, the skin does absorb what is applied to it. Therefore, it's important to use it exactly as prescribed by a healthcare provider.
- Risks: Although the topical form is generally considered safer than the oral form, it still carries potential risks, including serious infections and other severe side effects.

For more detailed information, you can visit the source: [Opzelura — Ruxolitinib Cream — DailyMed](https://www.MyEczemaTeam.com/treatments/opzelura).

September 20, 2024

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