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Real members of MyEczemaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Hi, my name is Jo. Just wondering if anyone of this Exzema team ever been on Methotrexate to calm their Exzema? If so, did you have effects?

A MyEczemaTeam Member asked a question 💭
Davenport, IA

I have extramarital Exzema over entire body, even my scalp & hate being on Prednisone so much.

January 30, 2023
 · 
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MyEczemaTeam

Hi Jo! Yes, according to the knowledge base, 139 people have indicated they have taken Methotrexate for eczema. Methotrexate is an immunosuppressant and is sometimes prescribed off-label to treat eczema.

Common Side Effects
- Nausea
- Vomiting
- Loss of appetite
- Temporary hair loss

Rare but Serious Side Effects
- Show Full Answer

Hi Jo! Yes, according to the knowledge base, 139 people have indicated they have taken Methotrexate for eczema. Methotrexate is an immunosuppressant and is sometimes prescribed off-label to treat eczema.

Common Side Effects:
- Nausea
- Vomiting
- Loss of appetite
- Temporary hair loss

Rare but Serious Side Effects:
- Infections
- Birth defects
- Seizures
- Damage to liver, lungs, or kidneys

It's important to discuss with your doctor and monitor any side effects you may experience.

July 23, 2024
A MyEczemaTeam Member

I use Methotrexate for rheumatoid arthritis. {It makes my hair fall out like crazy] It doesn't calm my eczema
Maybe what is on your scalp is not the same thing. I have seborrhea on my scalp, eczema on hands and face.
I would not want to be on prednisone at all, bad for bone breakage.

February 10, 2023

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